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The analysis of bacteria-host communications additionally involves in vivo number immune answers, and that can be controlled by germs, being these last potent tools for different immunotherapies. During the last years, tumour immunotherapies, mainly the usage of antibodies that target immune checkpoints [checkpoint inhibitors (CPI)], were a revolution in oncology, allowing the treating tumours usually with extremely bad prognosis. In identical course, germs inoculations have already be