https://www.selleckchem.com/pr....oducts/protac-tubuli
INTRODUCTION The relationships among PIK3CA mutations, medication use and tumor progression remains poorly understood. Aspirin use post-diagnosis may modify components of the PI3K pathway, including AKT and mTOR, and has been associated with lower risk of breast cancer recurrence and mortality. We assessed time to metastasis (TTM) and survival with respect to aspirin use and tumor PIK3CA mutations among women with metastatic breast cancer. METHODS Patients with hormone receptor positive, HER2 negative (HR+/HER2-) metas