https://www.selleckchem.com/pr....oducts/bodipy-493-50
2-fluorofucose (2FF) inhibits protein and cellular fucosylation. Afucosylation of IgG antibodies enhances antibody-dependent cell-mediated cytotoxicity by modulating antibody affinity for FcyRIIIa which can impact secondary T-cell activation. Immune responses towards most common solid tumors are dominated by a humoral immune response rather than the presence of tumor infiltrating cytotoxic T-cells. IgG antibodies directed against numerous tumor-associated proteins are found in the sera of both breast cancer patients and transgeni
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