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BACKGROUND Gaps persist in HIV testing, treatment, and prevention services for men, leading to higher attributable mortality compared to women. We sought to characterise HIV prevention knowledge, risk behaviours, and interest in pre-exposure prophylaxis (PrEP) among young men in rural South Africa. METHODS We conducted interviews with HIV-negative heterosexual men which were thematically analysed to identify key themes. RESULTS Among 31 participants, median age was 26 (IQR23-31), 77% were unemployed, 52% reported previous STI, 84% report