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The present study was conducted to examine antidiabetic effects of ethanolic extract [ ] and to investigate its effects on oxidative stress markers and the expression of TLR4, S100A4, Bax and Bcl-2 genes in the kidney of STZ-induced diabetic rats. Thirty six rats (weight 200-250g) were randomly divided into diabetes and control groups. Induction of diabetes was performed using STZ (55mg/kg.bw). Biochemical parameters and oxidative stress markers (SOD and MDA) were measured using spectrophotometry after 60days of treatment. The expressio