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To investigate the effectiveness and safety of homeopathic medicine Natrum muriaticum (LM2) for mild cases of COVID-19 in Primary Health Care. A randomized, two-armed (11), parallel, placebo-controlled, double-blind, clinical trial is being performed to test the following hypotheses H0 homeopathic medicines = placebo (null hypothesis) vs. H1 homeopathic medicines ≠ placebo (alternative hypothesis) for mild cases of COVID-19 in Primary Care. Setting Primary Care of São Carlos - São Paulo - Brazil. One hundred participants aged 18 years