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Treatment of Add in Adults Treatment for adults with add usually involves a combination of medications, life skills training and psychotherapy. The majority of patients respond to stimulant medicines like methylphenidate (Ritalin) and amphetamines, such as the lisdexamphetamine (Adderall XR) or extended-release mixed amphetamine salts. Stimulants may increase blood pressure and heart rate. Non-stimulants like atomoxetine and bupropion can also improve ADHD symptoms. Psychother