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Regular rats had been evaluated in terms of inflammatory nociception using the formalin test and for motor coordination using the rotarod test. To define the device underlying the activity of perospirone, the consequences of intrathecal pretreatment using the 5-HT1A receptor antagonist WAY-100635, the 5-HT2A/2C receptor agonist 1-(2,5-dimethoxy-4-iodophenyl)-aminopropane (DOI), therefore the dopamine D2 receptor agonist sumanirole on perospirone action were analyzed utilising the electronic von Fr