https://www.selleckchem.com/pr....oducts/CP-690550.htm
A nearly full-length version of Skp1 with this substitution (Skp1ΔF97E) behaved as a stable monomer at concentrations of ≤500 μM and actively bound a model FBP, mammalian Fbs1, which suggests that the dimeric state is not required for Skp1 to carry out a basic biochemical function. Finally, Skp1ΔF97E is expected to serve as a monomer model for high-resolution NMR studies previously hindered by dimerization.Two-dimensional (2D) Janus structures, which are totally different from prevailing 2D structures, are more interesting for photoca
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