https://www.selleckchem.com/pr....oducts/dinaciclib-sc
The first aromatic C-H silylation between arylphosphines and hydrosilanes enabled by ruthenium complex has been developed. The excellent ortho-selectivity was resulted from a four-membered metallacyclic intermediate involving phosphorus chelation. The developed system could be extended to benzylic C-H silylation of arylphosphines. Diverse silylated arylphosphines are produced, which exhibit broad functional group compatibility. Further functionalization of the products under mild conditions renders the formed compounds usef
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