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Only exercise resulted in increased levels of glutathione peroxidase (GPX) (12.2%, 8.8%) (p less then 0.05), reduced glutathione (GSH) (17.6%, 10.1%) (p less then 0.05), superoxide dismutase (SOD) (7.6%, 6.5%) (p less then 0.05) and malondialdehyde (MDA) (10.3%, 9.6%) (p less then 0.05), for both the placebo and caffeine groups respectively. In conclusion, our study highlighted that the consumption of 3 mg/kg caffeine could be an improving agent for the physical, cognitive, and psychological states without affecting the oxidative stress