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IL-2R on T cells upregulated both in wild-type and LAG-3 deficiency CLP mice. CONCLUSIONS LAG-3 diminish or anti-LAG-3 antibody blockade protected CLP mice from sepsis-associated immunodysfunction and maybe a new target for the treatment. © The Author(s) 2020. Published by Oxford University Press for the Infectious Diseases Society of America. All rights reserved. For permissions, e-mail journals.permissions@oup.com.The construction of robust, modular and compact DNA machinery facilitates us to build more intelligent and inge
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