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density correlated with motor function, suggesting a neuroprotective effect of the PMSC-ECM in prevention of paralysis. A first-in-human clinical trial of PMSCs in human fetal myelomeningocele repair is underway.The prosthesis loading force is an important factor for dental implant survival. Even if adequate osseointegration of the dental implant has been achieved, if the occlusal forces are not correctly distributed, lateral torque can be generated causing high stress on surrounding tissues. The stress value of implant prostheses could b