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Treatment For ADHD Psychosocial therapy is the main treatment for add. These medications include stimulants like amphetamine and methylphenidate, and nonstimulants like atomoxetine, viloxazine, guanfacine, and clonidine. Stimulant medication should not be used by patients who have active substance abuse problems but they can be considered in those who are in stable recovery. Combination therapy using antidepressants particularly SSRIs, is an alternative option. Stimulants Stimulants increase the levels of dopamine