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72%. Among all industrial sectors, the mining industry, manufacturing industry, power, heat, gas, and water production and supply industry, and the wholesale and retail industry, were the most heavily influenced. In general, the operating vent numbers of key polluting enterprises in China decreased by 24.68%, and the standardized NOx (w)5-day decreased by an average of -9.54 ± -6.00 due to the COVID-19 pandemic. The results suggest that COVID-19 significantly reduced the NOx emission levels of the key polluting enterprises in China.The