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To assess the relationship between poverty and pain-related interference. Data on a sample of 108,259 adults aged 18 and older from the Household Component of the Medical Expenditure Panel Survey (MEPS) from 2013-2017 were analyzed. I assess the odds of reporting any pain-related interference, as well as increasing levels of pain-related interference, using binary and ordinal logistic regression, respectively. After controlling for covariates, the analysis showed a significant association between poverty and pain-related interference, w