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Adult ADHD and Comorbid Disorders Many people with ADHD also suffer from comorbid disorders like major depressive disorder (Kessler and colleagues 2006). Many depressed patients are not able to respond well to medication and may be able to benefit from therapy. Neurotransmitters are brain chemicals that regulate and increase levels of certain brain chemicals. The most frequently prescribed stimulants include amphetamine, methylphenidate and similar drugs. Medicines A variety of medications used to treat ADHD in children c