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https://www.selleckchem.com/pr....oducts/fti-277-hcl.h
Xanthohumol (Xn) is the most abundant prenylated flavonoid in Hops ( L.), and exhibits a range of pharmacological activities. This study aimed to investigate the effect of Xn on TGF-β1-induced cardiac fibroblasts activation and elucidate the underlying mechanism. The cellTiter 96 AQueous one solution cell proliferation assay kit was adopted to determine the cell viability of cardiac fibroblasts, and the proliferation was detected through 5-ethynyl-2'-deoxyuridine (EdU) incorporation assay. The α-SMA protein expression was measured b