https://www.selleckchem.com/pr....oducts/pf-04620110.h
At the end of behavioral experiments, histological and biochemical evaluations were done on prepared spinal cord samples. RESULTS Isobologram results showed that combination therapy significantly increased the pain threshold comparing to injection of endomorphin-1 (EM) or muscimol alone. Histological studies indicated the increased expression of α2 subunits of GABA receptors, and NR1 subunits of NMDA receptors in the spinal cord. The combination therapy also increased the glutathione (GSH) and superoxide dismutase (SOD) level and de
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