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Pupal lethality and melanized pseudo-tumors were suppressed in Psc1 and esc2 backgrounds while polycomb group member mutations Pc1 and Su(z)123 and trithorax group member mutation TrlR85 enhanced the phenotype. Dfd, Ubx and abd-A are leukemogenic. Mutations in Polycomb and trithorax group members modulate the leukemogenic phenotype. Our RNAseq of Cg-Gal4 UAS-abd-A hemocytes may contain genes important to Hox gene induced leukemias.Leptospirosis is a neglected, widespread zoonosis caused by pathogenic species of the genus Leptospir
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