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https://www.selleckchem.com/pr....oducts/ecc5004-azd50
Based on MLST analyses the global population of is distributed in eight clades, of which Clade 2 includes the "hypervirulent" NAP1/RT027/ST01 strain along with various unexplored sequence types (STs). To clarify whether this clinically relevant phenotype is a widespread feature of Clade 2, we used the murine ileal loop model to compare the in vivo pro-inflammatory (TNF-α, IL-1β, IL-6) and oxidative stress activities (MPO) of five Clade 2 clinical isolates from sequence types (STs) 01, 41, 67, and 252. Besides, we infected Golden