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ADHD Treatment For Adults - Stimulant Medication Stimulant drugs like methylphenidate and dextroamphetamine are typically considered the as the first-line treatment for adults with ADHD. These drugs boost and balance levels of neurotransmitters, which are brain chemicals. Antidepressants and nonstimulant medicines like atomoxetine may be prescribed when stimulants aren't suitable for the patient due to other health problems or adverse effects. These medications are slower than st