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https://www.selleckchem.com/pr....oducts/ch4987655.htm
Activation of astrocytes contributes to synaptic remodelling, tissue repair and neuronal survival following traumatic brain injury (TBI). The mechanisms by which these cells interact to resident/infiltrated inflammatory cells to rewire neuronal networks and repair brain functions remain poorly understood. Here, we explored how TLR4-induced astrocyte activation modified synapses and cerebrovascular integrity following TBI. To determine how functional astrocyte alterations induced by activation of TLR4 pathway in inflammatory cells regu