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7, P = .022) and sarcopenia (HR 3.6, P = .019). Male gender was associated with worse progression-free survival (HR 2.6, P = .016). CONCLUSIONS Sarcopenia is associated with worse overall survival in patients with anal cancer. Further studies are indicated to determine if survival can be improved with increased attention to nutritional status in sarcopenic patients. © 2020 Wiley Periodicals, Inc.This study was aimed to explore the expression and biological function of circRNA_0005075 in gastric cancer (GC) progression and its und