https://www.selleckchem.com/pr....oducts/valemetostat-
01%) compared to tolerant (median 0.006%) and non-atopic donors (median 0.0015%, p=0.008). The majority of mAbs (74%, 29/39) bound specifically to Arah 2 and/or 6. Non-specific mAbs (9/1 were mainly derived from non-atopic controls. In allergic donors, 89% of heavy chain gene transcripts consisted of VH3 family genes, compared with only 54% in sensitized but tolerant and 63% of non-atopic donors. Additionally, certain HCDR3 sequence motifs were associated with allergy (n=4) or tolerance (n=3) upon hierarchical clustering
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