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The renal damage and histopathological changes in the kidney were based on microscopic evaluations. Results management of UD plant along side GM, in comparison to GM team, significantly decreased the quantities of plasma creatinine and BUN, urinary salt excretion, fractional removal of salt and potassium, and MDA amounts but somewhat enhanced creatinine clearance, urine osmolarity, renal circulation and FRAP levels. Conclusion The cotreatment of UD plant can attenuate