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The aim of this study was to screen the predisposed population and explore possible interactions between genetic polymorphisms and risk factors involved in the tumorigenesis and progression of ESCC (esophageal squamous cell carcinoma), in hope of identifying possible therapeutic targets along the way. Cases (1043) and controls (1315) were enrolled to evaluate the possible association between SNPs and ESCC risk. Subgroup analyses include variants, gender, age, smoking and drinking status. Among all three single locus polymorphisms of , on
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