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Meta-analysis was performed using data from two retrospective studies of 261 patients. Perioperative chemotherapy did not have a significant effect on survival and event-free survival. We weakly do not recommend perioperative chemotherapy in patients with non-metastatic synovial sarcoma≤5cm when R0 resection is acquired. There was no consensus concerning the role of perioperative chemotherapy in patients with synovial sarcoma5cm or those with ≤5cm who undergo R1 or R2 resection. 5 cm or those with ≤5 cm who undergo R1 or R2 resection.