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This informative article is protected by copyright. All rights reserved.Fine needle aspiration (FNA), the foundation of diagnosis in thyroid swellings, does not render a definitive diagnosis in about 20% to 30% of cases which are reported as indeterminate on cytology. Considering that the clinical management in thyroid rests on the chance of malignancy (ROM) in a given nodule, this difference between "benign" and "possibly malignant" assumes important medical impo