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After management, the lumbar spinal-cord enhancement of rats had been gathered for ELISA, Western blot and immunofluorescence analysis. Technical withdrawal threshold and thermal detachment latency results revealed that Lic-A dramatically attenuated CCI-evoked neuropathic discomfort in dose-dependent manner . Lic-A management also successfully blocked microglia activation. Moreover, Lic-A suppressed p38 phosphorylation together with launch of inflammatory elements such as f