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falciparum . Stereoisomeric ozonide 12b is 11-times more active than stereoisomeric ozonide 12a (IC 50 5.81 µM vs IC 50 65.18 µM). Current findings merit further investigation of ozonides as potential therapeutic agent for drug-resistant hepatocellular carcinoma. © 2020 WILEY-VCH Verlag GmbH Co. KGaA, Weinheim.On October 24, 2019, a marketing authorization valid through the European Union (EU) was issued for gilteritinib monotherapy for adult patients who have relapsed or refractory acute myeloid leukemia (AML) with an Fms-like tyrosine kinase 3 (FLT3