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First Line Treatment For ADHD in Adults Some people suffering from ADHD are able to use medication to manage their symptoms. The stimulants, like methylphenidate and amphetamine, are effective in boosting activity in brain areas that control attention and behavior. Other medications, such as the non-stimulant atomoxetine, and other antidepressants, work differently but are equally effective. Patients who are taking medication should visit their GP regularly to observe the effects on the body and adjust d