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Treatment of Add in Adults Treatment for adults with add typically involves a combination of medications, life skills training and psychotherapy. Most patients respond well to stimulant medications like methylphenidate (Ritalin) and amphetamines such as lisdexamphetamine (Adderall) or extended-release mixed amphetamine salts (Adderall XR). Stimulants can raise blood pressure and heartbeat. Nonstimulants such as atomoxetine or bupropion can also help to improve ADHD