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Treatment of Add Treatment for Add typically involves medication and psychosocial treatments. Treatments for ADHD may include stimulants like methylphenidate and amphetamine compounds or nonstimulant medications such as atomoxetine (Strattera), bupropion (Wellbutrin) and tricyclic antidepressants. If have a history of mood instability, mood-stabilizing drugs like clonidine (Catapres) and guanfacine(Kappvay) may be prescribed. Stimulants Stimulants affect the central nervous system to increase energy and alertness. They could be prescribed medications such as amph