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Analysis regarding the REP-TILs with flow- and mass-cytometry program mainly activated and classified effector memory T cells. REP-TILs revealed in vitro reactivity and phrase of inhibitory receptors, such LAG-3 and PD-1. Additionally, our information suggest that inclusion of ipilimumab therapy improves the T cell fold development during production, raise the level of CD8 T cell tumor reactivity, and positively impact the T mobile phenotype. We show that the combination of