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Treatment of Add in Adults Adults with add are typically treated using a combination of medication therapy, psychotherapy and life-skills training. The majority of patients respond well to stimulant drugs like methylphenidate (Ritalin) and amphetamines, like amphetamine lisdexamphetamine (Adderall) or extended-release mixed amphetamine salts (Adderall XR). The effects of stimulants can increase blood pressure and heartbeat. Non-stimulants such as atomoxetine, bupropion may also help impr