https://www.selleckchem.com/pr....oducts/CP-690550.htm
Among the core members of the injury-repressed gene module, we identified Plasmalemma vesicle-associated protein (PLVAP) as a protein amply expressed by mouse and human HSCs. PLVAP expression was suppressed in activated HSCs upon injury and may hence define hitherto unknown roles for HSCs in the regulation of microcirculatory exchange and its breakdown in chronic liver disease CONCLUSIONS Our study offers a single-cell resolved account of drug-induced injury of the mammalian liver and identifies key genes that may serve important role
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