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OBJECTIVES Depressive symptoms and cognitive impairment often concur in older persons. Differentiating the cause of cognitive impairment in older persons with Depressive Disorder (DD) from other diseases such as Alzheimer's Disease (AD) is challenging. The goal of this study was to characterize cognitive impairment in older persons with DD. DESIGN Cross-sectional retrospective observational clinical cohort study using patient records from 2014 to 2018. SETTING Gerontopsychiatric services of Ulm University at Bezirkskrankenhaus Günzburg