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Obeticholic acid (OCA) is a potent farnesoid X receptor (FXR) agonist approved for the procedure of primary biliary cholangitis. We investigated the effectiveness and protection of OCA in customers with PSC. METHODS AESOP was a phase II, randomized, double-blind, placebo-controlled, dose-finding study. Eligible customers had been 18 to 75 years old with a diagnosis of PSC and serum alkaline phosphatase (ALP) ≥2×ULN and complete bilirubin less then 2.5×ULN. Custo
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