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033; MinADC t = 2.635, p = 0.009) in rectal cancer, but no significant correlation with gender, age, and tumor location (p 0.05). The MinADC values showed a higher diagnostic efficacy in discriminating the well or poor differentiationof rectal cancer compared to MeanADC values, with a threshold value of ≥0.929 × 10 mm /s (sensitivity, 80%; specificity, 88.1%) or ≤0.752 × 10 mm /s (sensitivity, 94.1%; specificity, 74%). Both MeanADC values and MinADC values might be used as a quantitative parameter to evaluate the aggressiveness of r