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The median MDS-UPDRS part I, component II, component III, and PDQ-39-summary index results were 8, 10, 22, and 25, correspondingly. The ultimate stepwise multiple linear regression model revealed that feminine sex (standard partial regression coefficient β = 0.131, P less then 0.05) and baseline MDS-UPDRS part we (β = 0.272, P less then 0.01) and component II (β = 0.571, P less then 0.01) ratings significantly predicted the PDQ-39-SI ratings at the 2-year follow-up. CONCLUSIONS