https://www.selleckchem.com/pr....oducts/valaciclovir-
These functional effects highlight a cooperative down-modulation of MYCN and its down-stream targets, ALK and LIN28B, exerted by miR-34a and let-7b that reactivate regulatory networks leading to a favorable therapeutic response. These findings demonstrate a promising therapeutic efficacy of miR-34a and let-7b combined replacement and support its clinical application as adjuvant therapy for high-risk NB patients. © 2020 WILEY-VCH Verlag GmbH Co. KGaA, Weinheim.Concomitant chemo-radiotherapy (cCRT) with 60 Gy in 30 fraction
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