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In natural ecosystems, long-term detrimental effects of pesticides may occur at very low concentrations, below those considered safe by the governmental risk assessment. Mechanisms potentially responsible for this unexpected sensitivity include environmental stress-factors such as food deficiency. To understand this so called "effect-paradox", we investigated how food stress interacts with insecticide-induced biochemical fingerprints. Therefore, we measured metabolomic perturbations in Daphnia magna following a 24 h exposure to esfenval