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Patients in all three groups demonstrated similar visual pain scores when submitted to office hysteroscopy (Group 1 4.18 ± 3.1, Group 2 4.68 ± 2.9, group 3 4.45 ± 2.9, P = 0.59). Moreover, patients presented high acceptance scores of the procedure, similar between groups. We performed a subgroup analysis in patients in treatment for chronic pelvic pain and, in this subgroup, prior medication with diclofenac sodium isolated or associated with hyoscine were both effective in decreasing pain levels when compared to placebo (Group 1 6.0 ± 1.