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Objective A score to distinguish Takotsubo syndrome (TS) from acute coronary syndrome would be useful to facilitate appropriate patient investigation and management. This study sought to derive and validate a simple score using demographic, clinical and ECG data to distinguish women with non-ST elevation myocardial infarction (NSTEMI) from NSTE-TS. Methods The derivation cohort consisted of women with NSTE-TS (n=10 and NSTEMI (n=10. Logistic regression was used to derive the score using ECG values available on the postacute ward rou