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FMD correlated positively with HDL (p = 0.006) and negatively with disease duration (p ≤ 0.001). CIMT (p = 0.017) and FMD (p = 0.04) were significantly worse in active than inactive disease. Children with JIA have worse lipid profile, increased LVMi, CIMT, and reduced brachial artery FMD, suggestive of early cardiovascular dysfunction.In this commentary paper I try to make complementarily more discussion on two question. First, the target paper (Zagaria, Andò, Zennaro, 202 points out the lack of continuity in the concepts used
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