https://www.selleckchem.com/pr....oducts/ly3537982.htm
At the cellular level, high glucose stimulation increased CIDEC expression in renal tubular epithelial cells, accompanied by increased apoptosis and decreased autophagy. CIDEC gene silencing can improve autophagy and reduce apoptosis. At the molecular level, CIDEC gene silencing also decreased the expression of early growth response factor (EGR)1 and increased the expression of adipose triglyceride lipase (ATGL). CIDEC gene silencing may delay the progression of DN by restoring autophagy activity and inhibiting apoptosis with the part
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