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Adult ADHD and Comorbid Disorders Many people suffering from ADHD suffer from comorbid disorders, such as major depression (Kessler and colleagues, 2006). Many patients who are depressed aren't able to take medication and may be able to benefit from therapy. are brain chemicals that regulate and boost levels of certain brain chemicals. Drugs that stimulate the brain such as methylphenidate or amphetamine are frequently prescribed. Medications Adults are able to take many different drug