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https://www.selleckchem.com/pr....oducts/ly-411575.htm
Persistent antigen exposure leads to the accumulation of lymphocytes and subsequent tertiary lymphoid structures (TLS). We investigated the relationship of tumor microenvironment (TME) with respect to programmed death ligand 1 (PD-L1), its receptor programmed death 1 (PD-1), and TLS in upper tract urothelial carcinoma (UTUC) cases and compared them with UTUC associated with urothelial bladder carcinoma (UTUC-BCa). We retrospectively identified 72 patients with UTUC. Representative slides were reviewed, and TLS were counted. Immunohist