https://www.selleckchem.com/pr....oducts/idasanutlin-r
The deposition rate of small particles (1-1.5 μm) is more sensitive to the level of septal rapture than large particles (2.5-3 μm). Unexpectedly, more particles per unit area deposit on the outer wall and at the base of the subacinus than on the inner septal walls. The subacinus-averaged doses increase with progressing septal destructions, suggesting an escalating risk factor to the acinar health at the late stages of emphysema. OSA has been associated with reduced exercise capacity. Endothelial dysfunction and exercise-indu
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